대한흉부영상의학회 Weekly Chest Cases

Courtesy of Kyung-Nyeo Jeon, M.D. / Gyeongsang National University Hospital, Jinju, Korea
Age/Sex 50 / M
Chief ComplaintIncidentally found chest radiographic abnormality

Diagnosis: Diffuse large B-cell lymphoma was confirmed by a mediastinoscopicbiopsy of the mass. At immunohistochemical staining, CD20 and LCA were positive.
Radiologic Findings: Chest CT scans show a homogenously enhancing mediastinal mass located between SVC and trachea. (precontrast: 44HU → postcontrast: 52HU). SVC is smoothly compressed by the mass.
Brief Review: Intrathoracic malignant lymphoma can present as a mass in anterior, middle, or rarely posterior mediastinum. It may appear in this area as a part of the manifestations of the disseminated process or as a primary mediastinal disease. Intrathoracic disease is less common for NHL than for Hodgkin lymphoma. Filly et al. showed that thoracic involvement occurs in 43% (58/136) of patients with NHL and 17.2% (23/136) of these patients had a single enlarged lymph node. CT examinations can generally reveal the location, size and properties of a lesion. CT findings of NHL have been characterized as homogenous, enhanced solid masses that rarely develop necrosis.
References: 1. Filly R, Blank N, Castellino RA. Radiographic distribution of intrathoracic disease in previously untreated patients with Hodgkin뭩 disease and Non-Hodgkin뭩 lymphoma. Radiology 1976; 120: 277?1.
2. Harnsberger RH, Bragg GD,Osborn GA et al. Non-Hodgkin lymphoma of the head and neck: CT evaluation of nodal and extranodal site. AJR Am. J. Roentgenol. 1987; 149: 785?1.
Keywords: Mediastinum, Lymphproliferative disorder, Lymphoma,

- Akdeniz University School of Medicine, Radiology Dept Antalya, Turkey Gokhan Arslan
- Ulsan University Hospital, Ulsan, Korea Jong-Chang Jang
- China Medical University Hospital, Taiwan Jun-Jun Yeh

- Depart of radiology, Inje University Ilsan Paik Hospital, Korea Bae Geun Oh
- Inha University Hospital, Korea Seung Woo Choi
- Jikei University, Japan Shigeki Misumi
- KAUMS, Kashan, Iran Ebrahim razi
- CHRU Lille hopital calmette, France Toledano Manuel
- University of Colorado Health Sciences Center, Denver Colorado USA Jeff Grossman
- Apollo Clinic, Kandivali (west), Mumbai, India Jeshil R. Shah
- Sctimst, Trivandrum, Kerala, India Santhosh Kannath
- St. Mary's hospital, The Catholic University, Korea Soo Kyung Yoon
- Mackay Memorial Hospital, Tapei, Taiwan Chia-Fu Tsai
- ANNEMASSE, Polyclinique de SAVOIE, France Gay-Depassier Philippe
- Regional Imaging Riverina, Australia Rashid Hashmi
- ASCS, Safwa, Saudi Arabia Kalari Adinarayana
- Homs National Hospital, Homs - Syria Rami Abou Zalaf
- Kyunghee University Medical Center, Korea Su Youn Sim
- IRSA, La Rochelle, France Denis Chabassiere
- Yongsan Hospital, College of Medicine, Chung-Ang University, Korea Jae Seung Seo
- AIIMS,Delhi, India Ashish Gupta
- Doctors Hospital, Nassau, Bahamas N.B.S.Mani
- Hospital Sotiria, Athens, Greece Vasilios Tzilas

- Aditya imaging Centre, Sayajigunj, Gujarat, India Vivek Patel
- Kazipet, Warangal, A.P., India Pavankumar Vodithala
- Ewha Womans University MokDong Hospital, Korea Yoo Kyung Kim
- Deptt. of Radiodiagnosis and Imaging, PGIMER, Chandigarh, India Ram Prakash Galwa
- Chung Moo Hospital, Korea Jong Hyeon Mo
- Ealing hospital NHS Trust, London, U.K. Shekhar Banavali
- Nirman Diagnostic Centre, Mumbai, India Padma Kannan
- IRSA La Rochelle, France Jean-Luc BIGOT
- Daegu Fatima Hospital, Korea Tae-hun Kim
- CHU Grenoble, France Bing Fabrice

대한흉부영상의학회 Korean Society of Thoracic Radiology